Among registry patients with mitral valve regurgitation due to flail mitral leaflets, performance of early mitral surgery compared with initial medical management was associated with greater long-term survival and a lower risk of heart failure, with no difference in new-onset atrial fibrillation.
Suri, R. M., Vanoverschelde, J.-L., Grigioni, F., Schaff, H. V., Tribouilloy, C., Avierinos, J.-F., Barbieri, A., Pasquet, A., Huebner, M., Rusinaru, D., Russo, A., Michelena, H. I., & Enriquez-Sarano, M. (2013). Association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation due to flail mitral valve leaflets. JAMA : the journal of the American Medical Association, 310(6), 609-616. https://doi.org/10.1001/jama.2013.8643 (Original work published 2013)