Efficient and selective deprotection method for N-protected 2(3H)-benzoxazolones and 2(3H)-benzothiazolones
(2004) Tetrahedron — Vol. 60, n° 45, p. 10321-10324 (2004)
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- Cyclic carbamate flanked with heterocyclic or aliphatic moieties are frequently used in medicinal chemistry. The synthesis of derivatives bearing a free NH often requires the use of a protection method. A literature search reveals very few protection/deprotection methods for cyclic carbamates. In this paper, we described different methods applicable to 2(3H)-benzoxazolone and 2(3H)-benzothiazolone. (C) 2004 Elsevier Ltd. All rights reserved.
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Carato, P., Yous, S., Sellier, D., Poupaert, J., Lebegue, N., & Berthelot, P. (2004). Efficient and selective deprotection method for N-protected 2(3H)-benzoxazolones and 2(3H)-benzothiazolones. Tetrahedron, 60(45), 10321-10324. https://doi.org/10.1016/j.tet.2004.08.070 (Original work published 2004)