Database of bronchoalveolar lavage fluid proteins

Noel-Georis, Isabelle;Bernard, Alfred;Falmagne, Paul;Wattiez, Rudy
(2002) Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences — Vol. 771, n° 1-2, p. 221-236 (2002)

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Authors
  • Noel-Georis, IsabelleDepartment of Biological Chemistry, University of Mons-Hainaut, Avenue du Champs de Mars 6, B-7000 Mons, Belgium
    Author
  • Bernard, AlfredUCLouvain
    Author
  • Falmagne, PaulDepartment of Biological Chemistry, University of Mons-Hainaut, Avenue du Champs de Mars 6, B-7000 Mons, Belgium
    Author
  • Wattiez, RudyDepartment of Biological Chemistry, University of Mons-Hainaut, Avenue du Champs de Mars 6, B-7000 Mons, Belgium
    Author
Abstract
Bronchoalveolar lavage during fiberoptic bronchoscopy is extensively used for investigating cellular and biochemical alterations of the epithelial lining fluid in various lung disorders. Two-dimensional electrophoresis (2-DE) offers the possibility to simultaneously display and analyze proteins contained in bronchoalveolar lavage fluid (BALF). We present the current status of 2-DE of BALF samples with an updated listing of the proteins already identified and of their level and/or posttranslational alterations in lung disorders. Alternatives to 2-DE of BALF samples and future prospects of proteomics to unravel lung functions and pathologies are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.
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Noel-Georis, I., Bernard, A., Falmagne, P., & Wattiez, R. (2002). Database of bronchoalveolar lavage fluid proteins. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 771(1-2), 221-236. https://doi.org/10.1016/S1570-0232(02)00114-9 (Original work published 2002)