Living Donor Exchange Programs (LDEPs) in kidney transplantation—also known as kidney paired donation or crossover transplantation—emerged in the early 1990s as a way to overcome immunological barriers in sensitized patients against their living donor. Indeed, ABO blood group incompatibility or pre-existing donor-specific antibodies to HLA lead to the exclusion of at least one-third of healthy donors. [...]
Kanaan, N., Mourad, M., & Goffin, E. (2024). Living Donor Exchange Program in Kidney Transplantation: An Underexploited Organ Resource. Transplantation, 108(12), 2294-2295. https://doi.org/10.1097/TP.0000000000005202 (Original work published 2024)