Although the treatment of anal squamous carcinoma is primarily medical, abdomino-perineal resection remains the only alternative treatment if primary chemoradiotherapy is contraindicated or is unsuccessful. Salvage surgery for anal squamous carcinoma requires wide excision of the anal sphincter and permanent abdominal colostomy. Such major surgery in an irradiated field is associated with significant morbidity from delayed wound healingm, but this can be reduced by the use of myocutaneous flaps, whilst perineal colostomy allows a permanent abdominal stoma to be avoided. These techniques have been employed in the management of low rectal cancer with good oncological and functional results. However, there is little data on perineal colostomy and its feasibility in squamous carcinoma is limited by the extent of the perineal surgical resection.
Abbes Orabi, N., Chaouat, M., Léonard, D., Remue, C., Boccara, D., Mimoun, M., & Kartheuser, A. (2011). Salvage surgery for anal squamous carcinoma: Abdominoperineal resection, perineal colostomy. Colon & Rectum, 5(2), 72-81. https://doi.org/10.1007/s11725-011-0297-2 (Original work published 2011)