Physical stability of highly concentrated injectable drugs solutions used in intensive care units.

Closset, M;Hecq, Jean-Daniel;Soumoy, L;Simar, J;Galanti, Laurence;et.al.
(2017) Annales Pharmaceutiques Francaises — Vol. 75, n° 3, p. 185-188 (2017)

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Authors
  • Closset, M
    Author
  • Hecq, Jean-DanielUCLouvain
    Author
  • Soumoy, L
    Author
  • Simar, J
    Author
  • Galanti, LaurenceUCLouvain
    Author
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Abstract
The intensive care department of the institution use drug solutions within higher concentration to avoid fluid overload. The purpose of the study is to prove the physical stability of different injectable drugs within high concentration (amiodarone 25mg/mL, isosorbide 0.60mg/mL, lorazepam 0.16mg/mL, noradrenalin 0.120 and 0.240mg/mL, salbutamol 0.06mg/mL and sodium valproate 12mg/mL) to ensure the patients safety.
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Citations

Closset, M., Hecq, J.-D., Soumoy, L., Simar, J., Gonzalez, E., Charlet, L., Declave, C., Gillet, P., & Galanti, L. (2017). Physical stability of highly concentrated injectable drugs solutions used in intensive care units. Annales Pharmaceutiques Francaises, 75(3), 185-188. https://doi.org/10.1016/j.pharma.2016.12.004 (Original work published 2017)