Dialkyltin Derivatives of Dicarboxylic-acids - Synthesis, Characterization and Invitro Antitumor Properties
(1992) Heteroatom Chemistry — Vol. 3, n° 4, p. 449-452 (1992)
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- Abstract
- Diorganotin derivatives of dicarboxylic acids, including diethyltin propene-1,3-dicarboxylate, diethyltin homophthalate, and di-n-butyltin tetrafluorophthalate, were tested in vitro against two human tumor cell lines, MCF-7, a mammary tumor, and WiDr, a colon carcinoma. Most of these display lower inhibition doses ID50 than cis-platin. The synthesis and characterization of the last three compounds by Mossbauer spectroscopy, H-1, C-13 and/or Sn-119 NMR and mass spectrometry, are also presented.
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Gielen, M., Boualam, M., Meriem, A., Mahieu, B., Biesemans, M., & Willem, R. (1992). Dialkyltin Derivatives of Dicarboxylic-acids - Synthesis, Characterization and Invitro Antitumor Properties. Heteroatom Chemistry, 3(4), 449-452. https://doi.org/10.1002/hc.520030422 (Original work published 1992)