Sesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus
(2019) Journal of Natural Products — Vol. 82, n° 5, p. 1283-1291 (2019)
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- Authors
Stadler, Marc 
- Abstract
- During the course of searching for new anti-infective and other biologically active secondary metabolites from Kenyan asidiomycetes, 13 previously undescribed metabolites,(6R,7S,10R)-7,10-epoxy-7,11-dimethyldodec-1-ene-6,11-diol (1) and 12 sesquiterpenes named elgonenes A−L (2−13), and the known compound P-coumaric acid (14) were isolated from a basidiomycete collected in Mount Elgon Natural Reserve. The producing organism represents a new species of the genus Sanghuangporus, which is one of the segregates of the important traditional Asian medicinal mushrooms that were formerly known as the “Inonotus linteus” complex. The structure elucidation of compounds 1−13, based on 2D NMR spectroscopy, high-resolution mass spectrometry, and other spectral methods, and their antibacterial, antifungal, and cytotoxic activities are reported.
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Citations
Cheng, T., Chepkirui, C., Decock, C., Matasyoh, J. C., & Stadler, M. (2019). Sesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus. Journal of Natural Products, 82(5), 1283-1291. https://doi.org/10.1021/acs.jnatprod.8b01086 (Original work published 2019)