Data processing in PET

Bol, Anne
(1996) Physica Medica : an international journal devoted to the applications of physics to medicine and biology — Vol. 12, n° Suppl. 1, p. 83-87 (1996)

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  • Bol, AnneUCLouvain
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Abstract
Positron Emission Tomography (PET) allows the in vivo measurement of the regional activity distribution of an injected radioactive tracer labelled with positron emitters. Due to the possibility of an accurate attenuation correction, this technique allows the estimation of quantitative physiological parameters such as regional blood flow, metabolic rates of glucose or receptor density. In order to relate the activity distribution measured by PET to the physiological process of interest, appropriate biochemical models must be formulated, validated and adapted to practical use. These models form a mathematical representation which incorporates all a priori known informations on the process and constitute a framework for the interpretation of the measured PET data. This paper describes the principles and some applications of the compartmental analysis which is the most often used approach in PET.
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Bol, A. (1996). Data processing in PET. Physica Medica : an international journal devoted to the applications of physics to medicine and biology, 12(Suppl. 1), 83-87. https://hdl.handle.net/2078.5/69191 (Original work published 1996)