Genetic insights into rapid kidney function decline
(2021) Kidney International — Vol. 99, n° 4, p. 805-808 (2021)
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- Abstract
- Gorski et al. report a meta-GWAS of rapid kidney function decline in 42 longitudinal studies from the CKDGen Consortium and UK Biobank, amounting to more than 270'000 individuals with two eGFRcrea measurements. They identified genome-wide significant variants associated with two indexes of rapid kidney function decline, involving genes with a high potential for causality. These data increase our understanding of kidney function and risk of disease.
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Citations
Terzi, F., & Devuyst, O. (2021). Genetic insights into rapid kidney function decline. Kidney International, 99(4), 805-808. https://doi.org/10.1016/j.kint.2020.11.017 (Original work published 2021)