Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barre syndromes
(1998) Acta Neurologica Belgica — Vol. 98, n° 4, p. 322-326 (1998)
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- Abstract
- Anti-GQ1b antibodies were assayed by an enzyme-linked immunosorbent assay in sera from patients with non-neurological disorders (N = 20), and with various neurological disorders (N = 59), including nine cases of Miller Fisher syndrome, 16 cases of Guillain-Barre syndrome and one case of acute post-infectious ophthalmoparesis. Such antibodies were found in most cases (8 out of 9) of Miller Fisher syndrome and at very high titres, in one case of Guillain-Barre syndrome characterised by air initial ophthalmoparesis, and in the case of isolated post-infectious ophthalmoparesis. The latter was characterised by a long-lasting occurrence of these antibodies. Anti-GQ1b antibodies are specific for an immune-mediated neuropathy of the cranial, especially oculomotor, nerves.
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Citations
Goffette, S., Jeanjean, A., Pierret, F., Peeters, A., & Sindic, C. (1998). Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barre syndromes. Acta Neurologica Belgica, 98(4), 322-326. https://hdl.handle.net/2078.5/141001 (Original work published 1998)