Humoral responses to BNT162b2 SARS-CoV-2 and hepatitis B vaccines are associated in patients on maintenance hemodialysis: a single-center experience in Belgium

Van Regemorter, Elliott;Scohy, Anaïs;Morelle, Johann;Jadoul, Michel;Labriola, Laura
(2022) Clinical Kidney Journal — Vol. 15, n° 2, p. 363-365 (2022)

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Abstract
(en) Maintenance hemodialysis (HD) patients are at high risk for life-threatening coronavirus disease 2019 (COVID-19). Recent studies have documented a strong humoral response after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in this population, even in older patients, in contrast to kidney transplant recipients. Previous reports have also shown a poor humoral response after hepatitis B virus (HBV) vaccination in chronic kidney disease patients with comorbidities (e.g. older age, diabetes, immunosuppression). We therefore hypothesized that this weak response to the HBV vaccine could serve as a potential indicator of response to SARS-CoV-2 vaccination. However, data linking humoral responses to both vaccines remains scarce and contradictory [...].
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Citations

Van Regemorter, E., Scohy, A., Morelle, J., Jadoul, M., & Labriola, L. (2022). Humoral responses to BNT162b2 SARS-CoV-2 and hepatitis B vaccines are associated in patients on maintenance hemodialysis: a single-center experience in Belgium. Clinical Kidney Journal, 15(2), 363-365. https://doi.org/10.1093/ckj/sfab221 (Original work published 2022)