High amylase activity in pleural fluid and primary bronchogenic adenocarcinoma.

Devuyst, Olivier;Lambert, Michel;Scheiff, Jean-Marie;Francart, J.
(1990) The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology — Vol. 3, n° 10, p. 1217-1220 (1990)

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  • Lambert, MichelUCLouvain
    Author
  • Scheiff, Jean-MarieUCLouvain
    Author
  • Francart, J.
    Author
Abstract
We report a case of primary bronchogenic adenocarcinoma, complicated by pleural effusion, in which very high pleural amylase activity was found, whilst serum amylase was normal. Isoamylase determination showed a salivary-type amylase. Concerning the origin of this enzyme, ultrastructural study of the malignant cells obtained from the pleural fluid suggested a local amylase synthesis. The pathophysiological significance of electron-dense granules found in these cells is also discussed.
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Devuyst, O., Lambert, M., Scheiff, J.-M., & Francart, J. (1990). High amylase activity in pleural fluid and primary bronchogenic adenocarcinoma. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 3(10), 1217-1220. https://hdl.handle.net/2078.5/52956 (Original work published 1990)