Advances in the management of squamous cell carcinoma of the head and neck

Machiels, Jean-Pascal;Lambrecht, Maarten;Hanin, François-Xavier;Duprez, Thierry;Hamoir, Marc;et.al.
(2014) F1000prime reports — Vol. 6, p. 44 (2014)

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Authors
  • Machiels, Jean-PascalUCLouvain
    Author
  • Lambrecht, Maarten
    Author
  • Hanin, François-XavierUCLouvain
    Author
  • Duprez, ThierryUCLouvain
    Author
  • Grégoire, VincentUCLouvain
    Author
  • Schmitz, SandraUCLouvain
    Author
  • Hamoir, MarcUCLouvain
    Author
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Abstract
Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide. The main risk factors for cancers of the oral cavity, larynx, oropharynx, and hypopharynx are alcohol and tobacco use. In addition, the human papillomavirus (HPV) is an established cause of oropharyngeal cancer. An experienced multidisciplinary team is necessary for adequate management and optimal outcome. The treatment of locally advanced disease generally requires various combinations of radiotherapy, surgery, and systemic therapy, but despite this aggressive multimodal treatment, 40% to 60% of the patients will relapse. In this report, we will discuss recent advances in the management of SCCHN, including new developments in molecular biology, imaging, and treatment.
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Machiels, J.-P., Lambrecht, M., Hanin, F.-X., Duprez, T., Grégoire, V., Schmitz, S., & Hamoir, M. (2014). Advances in the management of squamous cell carcinoma of the head and neck. F1000prime reports, 6, 44. https://doi.org/10.12703/P6-44 (Original work published 2014)