In endometriosis development, local activation of estrogens appears to be important. STS and HSD17B1 inhibitors may therefore prove useful to treat the disease.
Colette, S., Defrere, S., Van Kerk, O., Van Langendonckt, A., Dolmans, M.-M., & Donnez, J. (2013). Differential expression of steroidogenic enzymes according to endometriosis type. Fertility and sterility, 1-8. https://doi.org/10.1016/j.fertnstert.2013.08.003 (Original work published 2013)