Transposición ovárica laparoscópica y criopreservación de tejido ovárico
(2002) Cuadernos de Medicina Reproductiva — Vol. 8, n° 1, p. 189-211 (2002)
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- Abstract
- Pelvic radiotherapy is frequently used to treat pelvic tumors in premenopausal women. It has already been stated that a dose of 5-20 Gy administered to the ovary is sufficient to completely impair gonadal function, whatever the age of the patient. Iatrogenic destruction of the follicular reserve by radiation therapy may be avoided by ovarian transposition into the pelvic gutter. Ovarian transposition performed by laparotomy was first described by McCall and colleagues in 1958 in patients treated for cervical carcinoma. Nowadays, ovarian suspension is laparoscopically performed before irradiation. However, it has also been demonstrated that, even if ovarian transposition is performed, it cannot be considered completely safe because patients receive infradiaphragmatic irradiation and, in many cases, there is an association between radiation and chemotherapy. For women who are to receive chemotherapy and/or radiotherapy, not only ovarian transposition but also cryopreservation of the ovarian tissue should be proposed, even if in vitro maturation of oocytes has not yet been proved to be routinely efficacious after cryopreservation. All the patients need to be informed of the long-term consequences of cancer and its therapy even if not all treatment causes infertility.
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Nisolle, M., De Hertogh, O., Qu, J. P., Squifflet, J.-L., & Donnez, J. (2002). Transposición ovárica laparoscópica y criopreservación de tejido ovárico. Cuadernos de Medicina Reproductiva, 8(1), 189-211. https://hdl.handle.net/2078.5/97514 (Original work published 2002)