D-lactic acidosis: an unusual cause of encephalopathy in a patient with short bowel syndrome
(2013) Acta Clinica Belgica — Vol. 68, n° 3, p. 229-231 (2013)
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- Authors
Thissen, Jean-Paul 
- Abstract
- A 24-year-old woman with a short bowel syndrome following post-ischemic small bowel resection, developed several episodes of lethargy, echolalia and ataxia. D-lactic acidosis was identified as the cause of neurological disturbances. This infrequent disorder can be precipitated by intake of a large amount of sugars, in patients with short bowel syndrome. It should be suspected in the presence of metabolic acidosis with increased anion gap and a normal level of L-lactic acid. The diagnosis relies on the specific dosage of D-lactic stereoisomer. Proper management involves rehydration, diet adaptation and oral administration of poorly absorbed antibiotics in order to modify the colonic flora responsible for D-lactic production.
- Affiliations
Citations
Dahlqvist, G., Guillen-Anaya, M. A., Vincent, M.-F., Thissen, J.-P., & Hainaut, P. (2013). D-lactic acidosis: an unusual cause of encephalopathy in a patient with short bowel syndrome. Acta Clinica Belgica, 68(3), 229-231. https://doi.org/10.2143/ACB.3217 (Original work published 2013)