Sources of the energy produced during a single isometric tetanus.
(1972) Hoppe-Seyler’s Zeitschrift fuer Physiologische Chemie — Vol. 353, n° 5, p. 734 (1972)
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- Frog sartorius muscles tetanized for 12 sec at 20°C in N2 split 15.4 ± 1.0 µmol phosphorylcreatine/g blotted weight, and 0.22 ± 0.19 µmol ATP/g; ADP and AMP concentrations did not change; lactate production amounted to 2.02 + 0.14 µmol/g; a-glycerophosphate increased by 0.89 ± 0.10 µmol/g and fructose 1.6-di-phosphate increased by 1.14 ±0.15 µmol/g (n=18). These reactions should produce together a heat which is evaluated to 190 mcal/g. However the observed heat production was much larger, 322 ± 13 mcal/g (n=9). Similar discrepancies were obtained for muscles in oxygen, or for muscles poisoned with iodoacetate. It is concluded that a large fraction of the heat produced during a long single tetanus is accounted for neither by phosphorylcreatine (PC) or ATP breakdown, nor by glycolytic or oxidative reactions
Citations
Maréchal, G., & Lebacq, J. (1972). Sources of the energy produced during a single isometric tetanus. Hoppe-Seyler’s Zeitschrift fuer Physiologische Chemie, 353(5), 734. https://hdl.handle.net/2078.5/214187 (Original work published 1972)