Chimeric antigen receptor T-cell therapy remains effective after exposure to bispecific antibodies. Comment to “Sequencing of cellular therapy and bispecific antibodies for the management of diffuse large B-cell lymphoma”

Crochet, Gilles;Houot, Roch
(2025) Haematologica — Vol. 110, n° 3, p. 808 (2025)

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  • Crochet, Gillesorcid-logoUCLouvain
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  • Houot, Roch
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Abstract
In the October issue of Haematologica, Melody and Gordon provided a comprehensive review of sequential immunotherapies in patients with relapsed or refractory (R/R) large B-cell lymphoma (LBCL). The authors claim that the efficacy of chimeric antigen receptor (CAR) T-cell therapy in patients previously exposed to bispecific antibodies (BsAb) is currently unknown. [...]
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Crochet, G., & Houot, R. (2025). Chimeric antigen receptor T-cell therapy remains effective after exposure to bispecific antibodies. Comment to “Sequencing of cellular therapy and bispecific antibodies for the management of diffuse large B-cell lymphoma”. Haematologica, 110(3), 808. https://doi.org/10.3324/haematol.2024.286353 (Original work published 2025)