Olfactory event-related potentials in infants

Schriever, Valentin A.;Góis-Eanes, Maria;Schuster, Benno;Huart, Caroline;Hummel, Thomas
(2014) The Journal of Pediatrics — Vol. 165, n° 2 (2014)

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Authors
  • Schriever, Valentin A.Technical University of Dresden
    Author
  • Góis-Eanes, MariaHospital Pedro Hispano, Matosinhos
    Author
  • Schuster, BennoTechnical University of Dresden
    Author
  • Author
  • Hummel, ThomasTechnical University of Dresden
    Author
Abstract
Objectives To evaluate olfactory event-related potentials (OERPs) as an objective measurement of olfactory function in infants. Study design OERPs to phenylethyl alcohol were measured in 13 infants, between 23 and 41 days of age. The odor was delivered with a computer-controlled olfactometer. Recording electrodes were applied using the 10-20 system. Data from electrodes Fz, Cz, Pz, C3, and C4 were analyzed by MatLab's Letswave toolbox (André Mouraux, Brussels, Belgium) using the canonical time-domain averaging as well as the time-frequency analyzing method. Results Ten of 13 infants finished the recording session. We observed OERPs in 7 of these 10 infants. Recordings were best in electrodes Fz and Cz. The N1 peak was visible at 328 ms followed by P2 at 505 ms. In addition, the time-frequency analysis had an increase in low frequencies (4-7 Hz) around 550 ms after odor presentation. Conclusions We were able to record OERPs in infants. The time-domain averaging as well as the time-frequency analysis was of value for data analysis. Copyright © 2014 Elsevier Inc. All rights reserved.
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Schriever, V. A., Góis-Eanes, M., Schuster, B., Huart, C., & Hummel, T. (2014). Olfactory event-related potentials in infants. The Journal of Pediatrics, 165(2). https://doi.org/10.1016/j.jpeds.2014.04.033 (Original work published 2014)