Delivery of genetic load during ex situ liver machine perfusion with potential for CRISPR-Cas9 gene editing: An innovative strategy for graft treatment.

Bonaccorsi Riani, Eliano;Gillooly, Andrew;Brüggenwirth, Isabel Ma;Martins, Paulo N
(2021) Hepatobiliary & Pancreatic Diseases International — Vol. 20, n° 5, p. 503-505 (2021)

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(en) TO THE EDITOR: Over the years, the shortage of suitable donor organs has challenged the transplant community in performing life-saving liver transplantation (LT). Recent reports from European and American liver transplant registries show persistently high waitlist mortality rates ranging between 10% and 18% [...]
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Bonaccorsi Riani, E., Gillooly, A., Brüggenwirth, I. M., & Martins, P. N. (2021). Delivery of genetic load during ex situ liver machine perfusion with potential for CRISPR-Cas9 gene editing: An innovative strategy for graft treatment. Hepatobiliary & Pancreatic Diseases International, 20(5), 503-505. https://doi.org/10.1016/j.hbpd.2021.04.006 (Original work published 2021)