[Acute Corticosteroid Myopathy and Critical Illness Polyneuropathy After Status-asthmaticus]
(1993) Revue Neurologique — Vol. 149, n° 10, p. 573-576 (1993)
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- Abstract
- A female patient treated by mechanical ventilation with high doses of pancuronium and methylprednisolone for status asthmaticus presented with acute total areflexic and severe amytrophic tetraplegia ; she died after multiple organ failure. Muscle biopsy confirmed the clinical diagnosis of << acute corticosteroid myopathy >>, precipitated by a corticosteroid or << disuse hypersensitivity >> after pancuronium. The electromyogram showed a critical illness polyneuropathy, secondary to multiple organ failure. Nerve biopsy was normal. The respective parts played by corticosteroids, curare-like derivatives and intensive care in the genesis of unexplained difficulty in weaning from the ventilator are discussed.
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Desmet, Y. (1993). [Acute Corticosteroid Myopathy and Critical Illness Polyneuropathy After Status-asthmaticus]. Revue Neurologique, 149(10), 573-576. https://hdl.handle.net/2078.5/146685 (Original work published 1993)