Four cases of chronic osteomyelitis of clavicle as primary manifestation of synovitis, acne, pustulosis, hyperostosis, osteomyelitis (SAPHO) are reported in adolescents. In all cases a typical radiographical evolution had been observed with progressive slow migration of sclerotic area from medial to lateral side of clavicle. Long-term evolution was alternation of remission and exacerbation but none of the patients healed.
Docquier, P.-L., Malghem, J., Mousny, M., & Rombouts, J.-J. (2006). Chronic osteomyelitis of clavicle as primary manifestation of SAPHO syndrome in adolescents: report of four cases and long-term evolution. Joint Bone Spine, 73(6), 756-759. https://doi.org/10.1016/j.jbspin.2006.01.020 (Original work published 2006)