Alternative synthesis of the PDE5 inhibitor RWJ387273 (R290629)

Lemaire, Sbastien;Willemsens, Bert;Marko, Istvan
(2007) Synlett : accounts and rapid communications in synthetic organic chemistry — n° 5, p. 709-712 (2007)

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  • Lemaire, Sbastien
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  • Willemsens, Bert
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  • Marko, IstvanUCLouvain
    Author
Abstract
An alternative synthesis of a PDE5 inhibitor is reported using a highly diastereoselective Pictet-Spengler reaction.
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Lemaire, S., Willemsens, B., & Marko, I. (2007). Alternative synthesis of the PDE5 inhibitor RWJ387273 (R290629). Synlett : accounts and rapid communications in synthetic organic chemistry, 5, 709-712. https://doi.org/10.1055/s-2007-970769 (Original work published 2007)