Nanoscale analysis of supported lipid bilayers using atomic force microscopy.

El Kirat, Karim;Morandat, Sandrine;Dufrêne, Yves
(2010) Biochimica et Biophysica Acta : international journal of biochemistry and biophysics — Vol. 1798, n° 4, p. 750-765 (2010)

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Authors
  • El Kirat, KarimLaboratoire de Biomécanique et Bioingénierie, UMR-CNRS 6600, Université de Technologie de Compiègne, BP 20529, F-60205 Compiègne Cedex, France
    Author
  • Morandat, SandrineLaboratoire de Génie Enzymatique et Cellulaire, UMR-CNRS 6022, Université de Technologie de Compiègne, BP 20529, F-60205 Compiègne Cedex, France
    Author
  • Dufrêne, YvesUCLouvain
    Author
Abstract
During the past 15years, atomic force microscopy (AFM) has opened new opportunities for imaging supported lipid bilayers (SLBs) on the nanoscale. AFM offers a means to visualize the nanoscale structure of SLBs in physiological conditions. A unique feature of AFM is its ability to monitor dynamic events, like bilayer alteration, remodelling or digestion, upon incubation with various external agents such as drugs, detergents, proteins, peptides, nanoparticles, and solvents. Here, we survey recent progress made in the area.
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El Kirat, K., Morandat, S., & Dufrêne, Y. (2010). Nanoscale analysis of supported lipid bilayers using atomic force microscopy. Biochimica et Biophysica Acta : international journal of biochemistry and biophysics, 1798(4), 750-765. https://doi.org/10.1016/j.bbamem.2009.07.026 (Original work published 2010)