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Clinical usefulness of the CSF β-amyloid Aβ1-42/Aβ1-40 ratio for Alzheimer's disease diagnosis: a retrospective study in a Belgian academic hospital.

Deltombe, Matthieu;Fillee, Catherine;Van Pesch, Vincent
(2022) Acta Neurologica Belgica — Vol. 122, n° 1, p. 245-247 (2022)

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Abstract
(en) DEAR EDITOR, Diagnosing Alzheimer’s disease (AD) can sometimes be challenging. In addition to clinical semiology and brain-imaging techniques, much emphasis has been put during the last years on the biological hallmarks of AD. The usual markers measured in cerebrospinal fluid (CSF) are Total-Tau (T-Tau), Phospo-Tau (P-Tau) and β-amyloid 1–42 peptide (Aβ42). The diagnostic performance of these CSF markers is quite acceptable when used and interpreted together [...]
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Deltombe, M., Fillee, C., & Van Pesch, V. (2022). Clinical usefulness of the CSF β-amyloid Aβ1-42/Aβ1-40 ratio for Alzheimer’s disease diagnosis: a retrospective study in a Belgian academic hospital. Acta Neurologica Belgica, 122(1), 245-247. https://doi.org/10.1007/s13760-021-01846-4 (Original work published 2022)