Synthesis of 5-dialkylamino-1,2,3-triazoles and 2-amino-1-azirines From Tertiary Amides

Henriet, Marielle;Houtekie, Marc;Techy, Brigitte;Touillaux, Roland;Ghosez, Léon
(1980) Tetrahedron Letters — Vol. 21, n° 2, p. 223-226 (1980)

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  • Author
  • Houtekie, MarcUCLouvain
    Author
  • Techy, BrigitteUCLouvain
    Author
  • Touillaux, RolandUCLouvain
    Author
  • Ghosez, LéonUCLouvain
    Author
Abstract
The reaction of sodium azide with β-monosubstituted-α-chloroenamines (generated from tertiary amides) yields either 5-dialkylamino-1,2,3-triazoles or 2-amino-1-azirines according to the basicity of the amine substituent.
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Citations

Henriet, M., Houtekie, M., Techy, B., Touillaux, R., & Ghosez, L. (1980). Synthesis of 5-dialkylamino-1,2,3-triazoles and 2-amino-1-azirines From Tertiary Amides. Tetrahedron Letters, 21(2), 223-226. https://doi.org/10.1016/S0040-4039(00)71421-3 (Original work published 1980)