Optimal management of hemophilic arthropathy and hematomas.

Lobet, Sébastien;Hermans, Cédric;Lambert, Catherine
(2014) Journal of Blood Medicine — Vol. 5, n° 17, p. 207-218 (2014)

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Abstract
Hemophilia is a hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX. Its bleeding complications primarily affect the musculoskeletal system. Hemarthrosis is a major hemophilia-related complication, responsible for a particularly debilitating chronic arthropathy, in the long term. In addition to clotting factor concentrates, usually prescribed by the hematologist, managing acute hemarthrosis and chronic arthropathy requires a close collaboration between the orthopedic surgeon and physiotherapist. This collaboration, comprising a coagulation and musculoskeletal specialist, is key to effectively preventing hemarthrosis, managing acute joint bleeding episodes, assessing joint function, and actively treating chronic arthropathy. This paper reviews, from a practical point of view, the pathophysiology, clinical manifestations, and treatment of hemarthrosis and chronic hemophilia-induced arthropathy for hematologists, orthopedic surgeons, and physiotherapists.
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Lobet, S., Hermans, C., & Lambert, C. (2014). Optimal management of hemophilic arthropathy and hematomas. Journal of Blood Medicine, 5(17), 207-218. https://doi.org/10.2147/JBM.S50644 (Original work published 2014)