These advances open perspectives for the understanding of cystogenesis in ADPKD, the mechanisms of osmoregulation, the role of polycystins in the brain, and the pleiotropic action of vasopressin.
Devuyst, O., & Torres, V. E. (2013). Osmoregulation, vasopressin, and cAMP signaling in autosomal dominant polycystic kidney disease. Current Opinion in Nephrology & Hypertension, 22(4), 459-470. https://doi.org/10.1097/MNH.0b013e3283621510 (Original work published 2013)