A new type of tetracyclic naphthoquinone, named isagarin (1), was isolated from the hexane extract of the roots of Pentas longiflora. On the basis of spectral and X-ray diffraction analysis this compound was identified as 1,4-epoxy-4-methyl-1,2,4,5-tetrahydronaphtho[2.3-d]oxepin-6,11-dione.
Van Puyvelde, L., Declercq, J.-P., El Hady, S., De Kimpe, N., & Feneau-Dupont, J. (1998). Isagarin, a new type of tetracyclic naphthoquinone from the roots of Pentas longiflora. Journal of Natural Products, 61(8), 1020-1021. https://doi.org/10.1021/np970589o (Original work published 1998)