Endoscopic ultrasound-guided gastroenterostomy with lumen-apposing metal stents: a retrospective multicentric comparison of wireless and over-the-wire techniques

Monino, Laurent;Perez-Cuadrado-Robles, Enrique;Gonzalez, Jean-Michel;Snauwaert, Christophe;Barthet, Marc;et.al.
(2023) Endoscopy — Vol. 55, n° 11, p. 991-999 (2023)

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Authors
  • Co-first author
  • Perez-Cuadrado-Robles, Enriqueorcid-logo
    Co-first author
  • Gonzalez, Jean-Michel
    Author
  • Snauwaert, Christophe
    Author
  • Author
  • Moreels, Tomorcid-logoUCLouvain
    Author
  • Barthet, Marcorcid-logo
    Author
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Abstract
(en) BACKGROUND: Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) using lumen-apposing metal stents (LAMSs) appears to be effective and safe in gastric outlet obstruction (GOO); however, the EUS-GE procedure is not standardized, with the use of assisted or direct methods still debated. The aim of this study was to compare the outcomes of EUS-GE techniques focusing on an assisted with orointestinal drain wireless endoscopic simplified technique (WEST) and the nonassisted direct technique over a guidewire (DTOG). METHOD: This was a multicenter European retrospective study involving four tertiary centers. Consecutive patients who underwent EUS-GE for GOO between August 2017 and May 2022 were included. The primary aim was to compare the technical success and adverse event (AE) rates of the different EUS-GE techniques. Clinical success was also analyzed. RESULTS: 71 patients (mean [SD] age 66.2 10 years; 42.3 % men; 80.3 % malignant etiology) were included. Technical success was higher in the WEST group (95.1 % vs. 73.3 %; estimate of relative risk from odds ratio (eRR) 3.2, 95 %CI 0.94-10.9; P = 0.01). The rate of AEs was lower in the WEST group (14.6 % vs. 46.7 %; eRR 2.3, 95 %CI 1.2-4.5; P = 0.007). Clinical success was comparable between the two groups at 1 month (97.5 % vs. 89.3 %). The median follow-up was 5 months (range 1-57). CONCLUSION: The WEST resulted in a higher technical success rate with fewer AEs, with clinical success comparable with the DTOG. Therefore, the WEST (with an orointestinal drain) should be preferred when performing EUS-GE.
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Citations

Monino, L., Perez-Cuadrado-Robles, E., Gonzalez, J.-M., Snauwaert, C., Alric, H., Gasmi, M., Ouazzani, S., Benosman, H., Deprez, P., Rahmi, G., Cellier, C., Moreels, T., & Barthet, M. (2023). Endoscopic ultrasound-guided gastroenterostomy with lumen-apposing metal stents: a retrospective multicentric comparison of wireless and over-the-wire techniques. Endoscopy, 55(11), 991-999. https://doi.org/10.1055/a-2119-7529 (Original work published 2023)