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Specific increase of genetic expression of parvalbumin in fast skeletal muscles of mdx mice
Parvalbumin mRNA was assayed by Northern blot analysis in muscles from normal and dystropic (mdx) mice. Its content was found to be specifically higher in mdx fast muscles than in control preparations. This suggests an increased expression of the protein in dystrophin-lacking fast fibres. A possible role in calcium homeostasis is discussed.
Gailly, P., Hermans, E., Octave, J.-N., & Gillis, J.-M. (1993). Specific increase of genetic expression of parvalbumin in fast skeletal muscles of mdx mice. FEBS Letters, 326(1-3), 272-274. https://doi.org/10.1016/0014-5793(93)81806-B (Original work published 1993)