Novel vancomycin resistance gene cluster in ST1486, Belgium, June 2021.

Xavier, Basil Britto;Coppens, Jasmine;De Koster, Sien;Rajakani, Sahaya Glingston;Matheeussen, Veerle;et.al.
(2021) Eurosurveillance (Print) — Vol. 26, n° 36, p. 2100767 [1-6] (2021)

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Authors
  • Xavier, Basil Britto
    Author
  • Coppens, Jasmine
    Author
  • De Koster, Sien
    Author
  • Rajakani, Sahaya Glingston
    Author
  • Mzougui, SamyUCLouvain
    Author
  • Anantharajah, AhalieyahUCLouvain
    Author
  • Matheeussen, Veerle
    Author
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Abstract
(en) We identified a novel van gene cluster in a clinical Enterococcus faecium isolate with vancomycin minimum inhibitory concentration (MIC) of 4 µg/mL. The ligase gene, vanP, was part of a van operon cluster of 4,589 bp on a putative novel integrative conjugative element located in a ca 98 kb genomic region presumed to be acquired by horizontal gene transfer from Clostridiumscidens and Roseburia sp. 499. Screening for van genes in E. faecium strains with borderline susceptibility to vancomycin is important.
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Xavier, B. B., Coppens, J., De Koster, S., Rajakani, S. G., Van Goethem, S., Mzougui, S., Anantharajah, A., Lammens, C., Loens, K., Glupczynski, Y., Goossens, H., & Matheeussen, V. (2021). Novel vancomycin resistance gene cluster in ST1486, Belgium, June 2021. Eurosurveillance (Print), 26(36), 2100767 [1-6]. https://doi.org/10.2807/1560-7917.ES.2021.26.36.2100767 (Original work published 2021)