Several indole alkaloids were tested by the agar dilution technique on a panel of human pathogenic fungi, yeasts, and dermatophytes. Our results indicate that the most active compounds possess a beta-carboline skeleton and that the presence of a 3-4 double bond enhances the activity. Our results also show that antifungal activities are not linked to the cytotoxic, antimicrobial or antiparasitic properties.
Quetin-Leclercq, J., Favel, A., Balansard, G., Regli, P., & Angenot, L. (1995). Screening for in vitro antifungal activities of some indole alkaloids. Planta Medica : natural products and medicinal plant research, 61(5), 475-477. https://doi.org/10.1055/s-2006-958141 (Original work published 1995)