Sirolimus and secondary skin-cancer prevention in kidney transplantation.

Euvrard, Sylvie; Morelon, Emmanuel; Rostaing, Lionel; Goffin, Eric; Brocard, Anabelle; Tromme, Isabelle; Broeders, Nilufer; del Marmol, Veronique; Chatelet, Valérie; Dompmartin, Anne; Kessler, Michèle; Serra, Andreas L; Hofbauer, Günther F L; Pouteil-Noble, Claire; Campistol, Josep M; Kanitakis, Jean; Roux, Adeline S; Decullier, Evelyne; Dantal, Jacques

doi:10.1056/NEJMoa1204166

Sirolimus and secondary skin-cancer prevention in kidney transplantation.

Euvrard, Sylvie

;

Morelon, Emmanuel

;

Rostaing, Lionel

;

Goffin, Eric

;

Dantal, Jacques

;et.al.

(2012) The New England journal of medicine — Vol. 367, n° 4, p. 329-339 (2012)

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Authors

Euvrard, Sylvie
Author
Morelon, Emmanuel
Author
Rostaing, Lionel
Author
Goffin, EricUCLouvain
Author
Tromme, IsabelleUCLouvain
Author
Dantal, Jacques
Author

Abstract

Switching from calcineurin inhibitors to sirolimus had an antitumoral effect among kidney-transplant recipients with previous squamous-cell carcinoma. These observations may have implications concerning immunosuppressive treatment of patients with cutaneous squamous-cell carcinomas. (Funded by Hospices Civils de Lyon and others; TUMORAPA ClinicalTrials.gov number, NCT00133887.).

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Euvrard, S., Morelon, E., Rostaing, L., Goffin, E., Brocard, A., Tromme, I., Broeders, N., del Marmol, V., Chatelet, V., Dompmartin, A., Kessler, M., Serra, A. L., Hofbauer, G. F. L., Pouteil-Noble, C., Campistol, J. M., Kanitakis, J., Roux, A. S., Decullier, E., & Dantal, J. (2012). Sirolimus and secondary skin-cancer prevention in kidney transplantation. The New England journal of medicine, 367(4), 329-339. https://doi.org/10.1056/NEJMoa1204166 (Original work published 2012)