Background: Central sensitization has been proposed as a pathophysiological pain mechanism in which central nervous system neurons become hyperexcitable, resulting in hypersensitivity to both noxious and non-noxious stimuli. The Central Sensitization Inventory (CSI) is a valid screening tool to help clinicians to identify patients with central sensitization. To date, no French version exists. Purpose: The aims of this study were to translate and cross-culturally adapt the CSI into French (CSI-Fr) and to investigate the main psychometric properties of the CSI-Fr. Methods: The CSI-Fr was developed using a standardized process of cross-cultural adaptation. Patients with chronic central sensitization pain (CS – Fibromyalgia) (n=40), patients with nociceptive pain (NP – acute ankle sprain) (n=40) and healthy controls (HC) (n=40) completed the CSI-Fr and 4 other questionnaires (Pain Catastrophizing Scale, Hospital Anxiety and Depression Scale, Brief Pain Inventory and SF-36). A confirmatory factor analysis was conducted based on the exploratory factor analysis carried out by Mayer et al. (2013); five alternative models relating to the structure of the questionnaire were tested. The ability of the questionnaires to discriminate between CS and HC was analysed and test-restest reliability for CS and HC was determined with a time interval of one week. The sensitivity and specificity of the established cutoff score of 40 were also assessed. Concurrent validity was calculated by correlating the CSI score with the scores from the 4 other questionnaires Results: The CFA demonstrated good fit indices for the 5 models (structural validity). There was a significant difference in CSI score between the patients with CP and the other groups (p<0.001); sensitivity was found to be 95% and specificity 90% using the cutoff score of 40 (discriminant validity). The total CSI score correlated with the scores of all the questionnaires (p<0.05) for CS, demonstrating good predictive validity. Test-retest reliability was excellent for both CS (ICC = 0.94) and HC (ICC = 0.91). Conclusion: The French version of the CSI was shown to be a reliable and discriminant tool for the screening of central sensitization. The good concurrent validity found supports the use of the CSI questionnaire for the assessment of patients with CS. Implications: The French version of the CSI can be used in clinical practice by French speaking patients.
Pitance, L., Piraux, E., Lannoy, B., Meuus, M., Berquin, A., Eeckhout, C., Dethier, V., Robertson, J., Meeus, M., & Roussel, N. (2016). CROSS CULTURAL ADAPTATION, RELIABILITY AND VALIDITY OF THE FRENCH VERSION OF THE CENTRAL SENSITIZATION INVENTORY. Manual Therapy, 25, 83-84. https://hdl.handle.net/2078.5/267112 (Original work published 2016)