Pseudomembranous enterocolitis in childhood.

Buts, Jean-Paul;Weber, A M;Roy, Cécile;Morin, C L
(1977) Gastroenterology — Vol. 73, n° 4 Pt 1, p. 823-827 (1977)

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  • Buts, Jean-PaulUCLouvain
    Author
  • Weber, A M
    Author
  • Roy, CécileUCLouvain
    Author
  • Morin, C L
    Author
Abstract
Pseudomembranous enterocolitis is reported in five children. The clinical syndrome, characterized by the acute onset of profuse diarrhea, occurred postoperatively in 2 patients. All the patients had received or were taking antibiotics (penicillin, ampicillin, clindamycin). The disease was severe in 4 persons who presented with hypoproteinemia. Related complications were edema, ascites, pleural effusion, septicemia and/or shock. The diagnosis was made on the basis of typical rectosigmoidoscopic findings. Despite intensive therapy 2 children died. The use of parenteral nutrition is advocated in severe cases with exudative enteropathy. When profuse diarrhea occurs postoperatively or does not rapidly subside with discontinuation of antibiotic therapy, a high index of suspicion should be maintained, even in children, for the possibility of pseudomembranous enterocolitis. An emergency rectosigmoidoscopy should be done in order to make an early diagnosis.
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Buts, J.-P., Weber, A. M., Roy, C., & Morin, C. L. (1977). Pseudomembranous enterocolitis in childhood. Gastroenterology, 73(4 Pt 1), 823-827. https://hdl.handle.net/2078.5/85964 (Original work published 1977)