Exploring the Significance of Cognitive Motor Dissociation on Patient Outcome in Acute Disorders of Consciousness.
(2024) Seminars in Neurology — Vol. 44, n° 3, p. 271-280 (2024)
Files
2024_Lejeune_Semin_Neurol_AB.pdf
Abstract PubMed
Open Access - Adobe PDF
- 103.68 KB
Details
- Authors
Cardone, Paolo 
- Abstract
- Cognitive motor dissociation (CMD) is characterized by a dissociation between volitional brain responses and motor control, detectable only through techniques such as electroencephalography (EEG) and functional magnetic resonance imaging. Hence, it has recently emerged as a major challenge in the assessment of patients with disorders of consciousness. Specifically, this review focuses on the prognostic implications of CMD detection during the acute stage of brain injury. CMD patients were identified in each diagnostic category (coma, unresponsive wakefulness syndrome/vegetative state, minimally conscious state minus) with a relatively similar prevalence of around 20%. Current knowledge tends to indicate that the diagnosis of CMD in the acute phase often predicts a more favorable clinical outcome compared with other unresponsive non-CMD patients. Nevertheless, the review underscores the limited research in this domain, probably at least partially explained by its nascent nature and the lack of uniformity in the nomenclature for CMD-related disorders, hindering the impact of the literature in the field.
- Affiliations
Citations
Lejeune, N., Fritz, P., Cardone, P., Szymkowicz, E., Vitello, M. M., Martial, C., Thibaut, A., & Gosseries, O. (2024). Exploring the Significance of Cognitive Motor Dissociation on Patient Outcome in Acute Disorders of Consciousness. Seminars in Neurology, 44(3), 271-280. https://doi.org/10.1055/s-0044-1785507 (Original work published 2024)