Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

de Meester, Carole;Timmermans, Aurélie;Balteau, Magali;Ginion, Audrey;Bertrand, Luc;et.al.
(2014) Cardiovascular Research — Vol. 101, n° 1, p. 20-29 (2014)

Files

RoleofAMP-activatedproteinkinaseinregulatinghypoxicsurvivalandproliferationofmesenchymalstemcells.pdf
  • Open Access
  • Adobe PDF
  • 692.28 KB
Download

Details

Authors
Show more
Abstract
MSCs resist hypoxia independently of AMPK whereas chronic AMPK activation inhibits MSC proliferation, p27 being involved in this regulation.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

de Meester, C., Timmermans, A., Balteau, M., Ginion, A., Roelants, V., Noppe, G., Porporato, P., Sonveaux, P., Viollet, B., Sakamoto, K., Feron, O., Horman, S., Vanoverschelde, J.-L., Beauloye, C., & Bertrand, L. (2014). Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells. Cardiovascular Research, 101(1), 20-29. https://doi.org/10.1093/cvr/cvt227 (Original work published 2014)