Internalization of Glimepiride and Glibenclamide in the Pancreatic B-cell
(1992) Acta Diabetologica : an international journal devoted to the study of clinical and experimental diabetes and metabolism — Vol. 29, n° 2, p. 113-114 (1992)
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- Abstract
- When rat pancreatic islets were exposed for 30 min at 37-degrees-C to tritiated glibenclamide (2.5 muM) or glimepiride (1.5 muM), internalization of these hypoglycaemic sulphonylureas in B and non-B cells was observed by autoradiography. In the B cell, the autoradiographic grains were often associated with secretory granules.
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Citations
Marynissen, G., Smets, G., Klöppel, G., Gerlache, L., & Malaisse, W. (1992). Internalization of Glimepiride and Glibenclamide in the Pancreatic B-cell. Acta Diabetologica : an international journal devoted to the study of clinical and experimental diabetes and metabolism, 29(2), 113-114. https://doi.org/10.1007/BF00572555 (Original work published 1992)