Methodologie Statistique à l'usage d'essais Pharmaco-cliniques dans les phénomènes addictifs
(1997) International Angiology : a journal on angiology — Vol. 20, p. 288-294 (1997)
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- Authors
Lehert, Philippe 
- Abstract
- (en) Using a disease specific QoL tool, we undertook a double blind placebo controlled study in patients with PAD to determine whether increase in Pain Free WD is reflected as an improvement in the Patient's QoL. Results: 235 patients were randomized . All patients completed the Clau-S at M0,M3,M6. statistical analysis was carried out on an Intention ot treat basis. Results: 108+112 were eligible for IT analysis. Multivariate Analysis of Covariance in adjusting for baseline conditions gave statistical evidence of a significant increase of QoL on the 6 considered dimensions of Clau-S. Conclusion: ManCoVA is the most powerful statistical test to assess multivariate QoL taking into account correlated value of baseline, 2) Naftidrofuryl significantly increases QoL on PAOD patients.
- Affiliations
Louvain School of Management
Citations
D’Hooge, D., Clement, D. L., & Lehert, P. (1997). Methodologie Statistique à l’usage d’essais Pharmaco-cliniques dans les phénomènes addictifs. International Angiology : a journal on angiology, 20, 288-294. https://hdl.handle.net/2078.5/129489 (Original work published 1997)