The BSMO expert panel recommendations on renal cell carcinoma management: 2025 update
(2026) Belgian Journal of Medical Oncology — p. 20 (2026)
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- Abstract
- The BSMO expert panel recommendations on renal cell carcinoma management: 2025 update SUMMARY The management of renal cell carcinoma is evolving rapidly. Here, the BSMO expert panel discusses recent advances focusing on systemic therapies, and provides guidelines adapted to the Belgian context. INTRODUCTION The Belgian Society of Medical Oncology (BSMO) renal cancer expert panel first published its recommendations for the management of renal cell carcinoma (RCC) in 2015, followed by regular updates.1–3 These recommendations are based on international guidelines and phase III trial data, while also considering the specificities of the Belgian health- care system. This updated overview integrates the latest evidence from pivotal trials, with the aim to provide a con- cise, practical guide to support clinical decision-making in real-world Belgian practice. EPIDEMIOLOGY In 2022, 2,076 new cases of RCC were reported in Belgium, including 1,377 men and 699 women (2:1 ratio), with a median age at diagnosis of 68 and 70 years respectively. The majority of patients (63%) were diagnosed with stage I disease, while 9% presented with stage II, 13% with stage III, and 15% with stage IV. Although the incidence of kidney cancer is increasing, mortality rates continue to decline. In 2021, 512 deaths were attributed to RCC, corresponding to a 5-year survival rate of 79.4% after initial diagnosis.4
- Affiliations
CHU de Liège, Liège, Belgium Department of Medical Oncology Leuven Cancer Institute, Leuven University Hospital, Leuven, Belgium Department of General Medical Oncology University Hospital Leuven, Leuven, Belgium Department of Pathology Kortrijk Cancer Centre, General Hospital AZ Groeninge, Kortrijk, Belgium Department of Medical Oncology General Hospital AZ Groeninge, Kortrijk, Belgium; Department of Human Structure and Repair, Ghent University, Ghent, Belgium Department of Radiation Oncology University Hospital Antwerp, Edegem, Belgium Department of Medical Oncology University Hospital Ghent, Ghent, Belgium Department of Medical Oncology
Citations
Gilon, P., Beuselinck, B., Baldewijns, M., Debruyne, P., Seront, E., Sundahl, N., Verbiest, A., Rottey, S., & Gennigens, C. (2026). The BSMO expert panel recommendations on renal cell carcinoma management: 2025 update. Belgian Journal of Medical Oncology, 20. https://hdl.handle.net/2078.5/277567 (Original work published 2026)