• Deintensifying treatment is suggested when anti-hyperglycaemic treatment places patient at risk of adverse events, or when the benefit that can be expected from it is negligible. • A few studies have shown that reducing the intensity of treatment can be carried out without risk, but no benefits have yet been demonstrated yet. • Deintensification of diabetes treatment is currently limited to glucose-lowering treatments. • Algorithms exist for the practical management of glucose-lowering treatment deintensification. • Treatments with a high risk of hypoglycaemia (such as sulfonylureas) should be stopped as a priority in patients for whom deintensification is suggested. • The use of adequate resources to educate patients and healthcare professionals should be promoted, in order to enable these recommendations to be properly implemented.
Christiaens, A. (2025). 17 - Deintensification of therapy. In Alan Sinclair, Ahmed Abdelhafiz (ed.), Care of Older People with Diabetes - A Manual for Healthcare Practice (6th ed., p. p. 448). Wiley-Blackwell. https://hdl.handle.net/2078.5/236981