OBJECTIVES: Autoimmune pancreatitis (AIP) represents a complex immune-mediated pancreas disorder. Pediatric AIP (P-AIP) is rare. We have recently summarized the characteristic features of P-AIP. We now aim to develop recommendation statements to standardize the diagnostic and therapeutic approach to P-AIP and facilitate future research in the field. METHODS: A panel of pediatric gastroenterologists participating in the International Study Group of Pediatric Pancreatitis: In search for a cuRE (INSPPIRE) was formed to discuss and then vote on 15 recommendation statements. A consensus of at least 80% was obtained following 3 voting rounds and revision of the statements. RESULTS: We have now generated 15 statements to help standardize the approach to diagnosis and management of P-AIP. CONCLUSIONS: The first P-AIP recommendation statements developed by the INSPPIRE group are intended to bring standardization to the diagnosis and treatment of this rare childhood disorder. These statements may help guide a uniform approach to patient care and facilitate future research studies.
Scheers, I., Palermo, J. J., Freedman, S., Wilschanski, M., Shah, U., Abu-El-Haija, M., Barth, B., Fishman, D. S., Gariepy, C., Giefer, M. J., Heyman, M. B., Himes, R. W., Husain, S. Z., Lin, T. K., Liu, Q., Lowe, M., Mascarenhas, M., Morinville, V., Ooi, C. Y., et al. (2018). Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood. Journal of Pediatric Gastroenterology and Nutrition, 67(2), 232-236. https://doi.org/10.1097/MPG.0000000000002028 (Original work published 2018)