In vitro evaluation of vena cava filters

Hammer, Frank;Rousseau, Herve P.;Joffre, Francis G.;Sentenac, Bernard P.;Barthelemy, Robert P.;et.al.
(1994) Journal of Vascular and Interventional Radiology — Vol. 5, n° 6, p. 869-876 (2021)

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Authors
  • Hammer, FrankUCLouvain
    Author
  • Rousseau, Herve P.
    Author
  • Joffre, Francis G.
    Author
  • Sentenac, Bernard P.
    Author
  • Barthelemy, Robert P.
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Abstract
The authors tested in vitro nine caval filters to evaluate clot-trapping capacity and transfilter pressure gradients under varying experimental conditions. The filtering efficiency of the stainless-steel Greenfield filter was evaluated in a modified flow model. A total of 2,100 clots were injected. In addition, controlled parameters simulating in vivo conditions were selected to appreciate clot-trapping capacity and pressure gradients for nine filters in horizontal and vertical positions, by using small (3 x 30 mm) and medium-sized (5 x 30 mm) clots. Statistical evaluation was performed for 3,600 clot deliveries. Depending on experimental conditions, the clot-trapping capacity of the Greenfield filter varied greatly (0%-78%) by using small and medium clots. Bird's Nest and Simon nitinol filters demonstrated the highest filtering efficiency (94%-100%) for small clots. Medium clots were effectively captured by Bird's Nest, Simon nitinol, Antheor, and Günther Tulip filters (79%-100%). Experimental parameters influence a filter's clot-trapping capacity. Bird's Nest filters demonstrated the highest clot-trapping capacity.
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Citations

Hammer, F., Rousseau, H. P., Joffre, F. G., Sentenac, B. P., Tran-Van, T., & Barthelemy, R. P. (1994). In vitro evaluation of vena cava filters. Journal of Vascular and Interventional Radiology, 5(6), 869-876. https://doi.org/10.1016/s1051-0443(94)71627-4 (Original work published 2021)