Metastases from unknown primary tumor: PET-FDG as initial diagnostic procedure?
(2000) Clinical Positron Imaging — Vol. 3, n° 4, p. 137-141 (2000)
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- Purpose: To analyze the efficacy and impact on management of PET-FDG in patients with metastases from unknown primary tumor. Procedures: Retrospective analysis of 24 patients referred to the PET center for metastasis of unknown primary after a negative imaging workup. PET results were validated by means of oriented imaging, follow-up or biopsy when ethically justified. Results: PET identified the primary tumor in 13/24 (54%) of patients: breast (n = 1), lung (n = 9), colon (n = 1), stomach (n = 1) and mouth (n = 1). The false positive rate of PET was 21% (5/24). PET was shown to affect the management of 10/24 patients (42%). Conclusion: Whole body PET-FDG was more effective than conventional imaging methods in detecting unknown primary tumors. PET altered patient management in 42% of cases. PET should be performed prior to other investigations in such patients and could avoid unnecessary and often unfruitful diagnostic procedures. Copyright © 2000 Elsevier Science Inc. All rights reserved.
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Lonneux, M., & Reffad, A. (2000). Metastases from unknown primary tumor: PET-FDG as initial diagnostic procedure? Clinical Positron Imaging, 3(4), 137-141. https://doi.org/10.1016/S1095-0397(00)00053-4 (Original work published 2000)