We set out to investigate whether MRI-visible centrum semiovale perivascular spaces (CSO-PVS), a potential biomarker of impaired interstitial fluid drainage in sporadic cerebral amyloid angiopathy, is associated with cortical superficial siderosis (cSS), reflecting recurrent hemorrhage from severe leptomeningeal and superficial cortical vascular amyloid.
Charidimou, A., Jäger, R. H., Peeters, A., Vandermeeren, Y., Laloux, P., Baron, J.-C., & Werring, D. J. (2014). White matter perivascular spaces are related to cortical superficial siderosis in cerebral amyloid angiopathy. Stroke : a journal of cerebral circulation, 45(10), 2930-2935. https://doi.org/10.1161/STROKEAHA.114.005568 (Original work published 2014)