C(16)-methyl corticosteroids are far less allergenic than the non-methylated molecules.

Baeck, Marie;Chemelle, Julie-Anne;Rasse, Catherine;Terreux, Raphaël;Goossens, An
(2011) Contact dermatitis — Vol. 64, n° 6, p. 305-312 (2011)

Files

101111_j1600-0536201101874x_C16methylcoerticosteroidsarelessfarallergenicthanthenonmethylatedmolecules.pdf
  • Restricted Access
  • Adobe PDF
  • 826.51 KB
Request a copy

Details

Authors
Abstract
C(16)-methyl substitution, interfering with protein binding, and halogenation, seem to reduce the allergenicity of corticosteroid molecules. Hence, when indicated, C(16)-methylated corticosteroids should be preferentially prescribed.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Baeck, M., Chemelle, J.-A., Rasse, C., Terreux, R., & Goossens, A. (2011). C(16)-methyl corticosteroids are far less allergenic than the non-methylated molecules. Contact dermatitis, 64(6), 305-312. https://doi.org/10.1111/j.1600-0536.2011.01874.x (Original work published 2011)