Neonatal acute myeloid leukemia in an infant whose mother was exposed to diethylstilboestrol in utero.
(2009) Pediatric Blood & Cancer — Vol. 53, n° 2, p. 220-222 (2009)
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- Abstract
- We report on an acute myeloid leukemia in a neonate whose mother was exposed to diethylstilboestrol in utero. The newborn presented with leukemia cutis, hemorrhagic skin lesions, hyperleucocytosis and disseminated intravascular coagulation. A bone marrow examination confirmed the diagnosis of acute monocytic leukemia with a t(11;19) MLL-ELL fusion transcript. Chemotherapy was initiated but the child developed a bilateral pulmonary infection that led to fatal respiratory distress. This case shows acute myeloid leukemia and the third pediatric leukemia reported after maternal diethylstilboestrol exposure. Pediatr Blood Cancer (c) 2009 Wiley-Liss, Inc.
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Citations
Chantrain, C., Sauvage, D., Brichard, B., Dupont, S., Poirel, H., Ameye, G., De Weer, A., Vandenberghe, P., Detaille, T., Anslot, C., Clément de Cléty, S., & Vermylen, C. (2009). Neonatal acute myeloid leukemia in an infant whose mother was exposed to diethylstilboestrol in utero. Pediatric Blood & Cancer, 53(2), 220-222. https://doi.org/10.1002/pbc.22040 (Original work published 2009)