(en) [Psoriasis and pregnancy in the era of biologics. Case report of ustekinumab treatment during pregnancy] We report the case of a successful delivery following exposure to ustekinumab during pregnancy. Though psoriasis is not uncommon in pregnant women, its treatment may prove challenging during pregnancy, especially in severe psoriasis cases. While the disease usually improves during pregnancy, its treatment must often be continued. Besides local treatment, UVB phototherapy remains the treatment of choice in moderate-to-severe psoriasis. In patients requiring a systemic treatment, biologics can be considered. Whereas limited safety results are available from studies, various follow-up registers provide reassuring data. Unexpected exposure to biologics during the first trimester of pregnancy proves unproblematic.
Fierens, H., & Baeck, M. (2016). Psoriasis et grossesse à l’heure des traitements biologiques : À propos d’un cas de grossesse sous ustekinumab. Louvain médical, 135(4), 231-235. https://hdl.handle.net/2078.5/181858 (Original work published 2016)